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The Role of Microglia in Inherited White-Matter Disorders and Connections to Frontotemporal Dementia

Microglia play a critical but poorly understood role in promoting white-matter homeostasis. In this review, we leverage advances in human genetics and mouse models of leukodystrophies to delineate our current knowledge and identify outstanding questions regarding the impact of microglia on central n...

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Detalles Bibliográficos
Autores principales: Sirkis, Daniel W, Bonham, Luke W, Yokoyama, Jennifer S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8020808/
https://www.ncbi.nlm.nih.gov/pubmed/33833548
http://dx.doi.org/10.2147/TACG.S245029