Role of Electrostatic Hotspots in the Selectivity of Complement Control Proteins Toward Human and Bovine Complement Inhibition

Poxviruses are dangerous pathogens, which can cause fatal infection in unvaccinated individuals. The causative agent of smallpox in humans, variola virus, is closely related to the bovine vaccinia virus, yet the molecular basis of their selectivity is currently incompletely understood. Here, we exam...

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Detalles Bibliográficos
Autores principales: Narkhede, Yogesh B., Gautam, Avneesh K., Hsu, Rohaine V., Rodriguez, Wilson, Zewde, Nehemiah T., Harrison, Reed E. S., Arantes, Pablo R., Gaieb, Zied, Gorham, Ronald D., Kieslich, Chris, Morikis, Dimitrios, Sahu, Arvind, Palermo, Giulia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Molecular Biosciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8020814/
https://www.ncbi.nlm.nih.gov/pubmed/33829039
http://dx.doi.org/10.3389/fmolb.2021.618068

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8020814/
https://www.ncbi.nlm.nih.gov/pubmed/33829039
http://dx.doi.org/10.3389/fmolb.2021.618068

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