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Structural basis of the activation of a metabotropic GABA receptor

Metabotropic γ-aminobutyric acid receptors (GABA(B)) are involved in the modulation of synaptic responses in the central nervous system and are implicated in various neuropsychological conditions, ranging from addiction to psychosis(1). GABA(B) belongs to G protein-coupled receptor class C, and its...

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Detalles Bibliográficos
Autores principales: Shaye, Hamidreza, Ishchenko, Andrii, Lam, Jordy Homing, Han, Gye Won, Xue, Li, Rondard, Philippe, Pin, Jean-Philippe, Katritch, Vsevolod, Gati, Cornelius, Cherezov, Vadim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8020835/
https://www.ncbi.nlm.nih.gov/pubmed/32555460
http://dx.doi.org/10.1038/s41586-020-2408-4