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Structural basis of the activation of a metabotropic GABA receptor
Metabotropic γ-aminobutyric acid receptors (GABA(B)) are involved in the modulation of synaptic responses in the central nervous system and are implicated in various neuropsychological conditions, ranging from addiction to psychosis(1). GABA(B) belongs to G protein-coupled receptor class C, and its...
Autores principales: | Shaye, Hamidreza, Ishchenko, Andrii, Lam, Jordy Homing, Han, Gye Won, Xue, Li, Rondard, Philippe, Pin, Jean-Philippe, Katritch, Vsevolod, Gati, Cornelius, Cherezov, Vadim |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8020835/ https://www.ncbi.nlm.nih.gov/pubmed/32555460 http://dx.doi.org/10.1038/s41586-020-2408-4 |
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