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Alantolactone inhibits stem-like cell phenotype, chemoresistance and metastasis in PC3 cells through STAT3 signaling pathway

BACKGROUND AND PURPOSE: Cancer stem cells (CSCs), as the subpopulation of cancer cells, are associated with carcinogenesis, chemoresistance, and metastasis in malignancies. Also, CSCs are considered as the major reason for treatment failure in prostate cancer (PCa). Alantolactone (ALT), exerts antic...

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Detalles Bibliográficos
Autores principales: Babaei, Ghader, Khadem Ansari, Mohammad Hassan, Aziz, Shiva Gholizadeh-Ghaleh, Bazl, Masoumeh Rajabi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8020850/
https://www.ncbi.nlm.nih.gov/pubmed/33828598
http://dx.doi.org/10.4103/1735-5362.301340