Cargando…

Alantolactone inhibits stem-like cell phenotype, chemoresistance and metastasis in PC3 cells through STAT3 signaling pathway

BACKGROUND AND PURPOSE: Cancer stem cells (CSCs), as the subpopulation of cancer cells, are associated with carcinogenesis, chemoresistance, and metastasis in malignancies. Also, CSCs are considered as the major reason for treatment failure in prostate cancer (PCa). Alantolactone (ALT), exerts antic...

Descripción completa

Detalles Bibliográficos
Autores principales:	Babaei, Ghader, Khadem Ansari, Mohammad Hassan, Aziz, Shiva Gholizadeh-Ghaleh, Bazl, Masoumeh Rajabi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Wolters Kluwer - Medknow 2020
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8020850/ https://www.ncbi.nlm.nih.gov/pubmed/33828598 http://dx.doi.org/10.4103/1735-5362.301340

Ejemplares similares

Alantolactone and ZnO nanoparticles induce apoptosis activity of cisplatin in an ovarian cancer cell line (SKOV3)
por: Alipour, Shahriar, et al.
Publicado: (2022)

Alantolactone triggers oxeiptosis in human ovarian cancer cells via Nrf2 signaling pathway
por: Nasirzadeh, Mahdieh, et al.
Publicado: (2023)

The protective impact of betaine on the tissue structure and renal function in isoproterenol‐induced myocardial infarction in rat
por: Ghartavol, Mohammad Maram, et al.
Publicado: (2019)

Evaluating the effect of Alantolactone on the expression of N-cadherin and Vimentin genes effective in epithelial-mesenchymal transition (EMT) in breast cancer cell line (MDA-MB-231)
por: Naderi, Roya, et al.
Publicado: (2022)

Critical roles of TLRs on the polarization of mesenchymal stem cells for cell therapy of viral infections: a notice for COVID-19 treatment
por: Gholizadeh-Ghaleh Aziz, Shiva, et al.
Publicado: (2021)

Revealed pathophysiological mechanisms of crosslinking interaction of affected vital organs in COVID-19
por: Rasmi, Yousef, et al.
Publicado: (2021)

The human amniotic fluid mesenchymal stem cells therapy on, SKOV3, ovarian cancer cell line
por: Gholizadeh‐Ghaleh Aziz, Shiva, et al.
Publicado: (2019)

The role of microRNAs in COVID-19 with a focus on miR-200c
por: Sodagar, Hadi, et al.
Publicado: (2022)

Alantolactone alleviates collagen-induced arthritis and inhibits Th17 cell differentiation through modulation of STAT3 signalling
por: Chen, Hsiang-Lai, et al.
Publicado: (2021)

Selective STAT3 Inhibitor Alantolactone Ameliorates Osteoarthritis via Regulating Chondrocyte Autophagy and Cartilage Homeostasis
por: Pei, Wenbin, et al.
Publicado: (2021)

Alantolactone Induces Apoptosis in HepG2 Cells through GSH Depletion, Inhibition of STAT3 Activation, and Mitochondrial Dysfunction
por: Khan, Muhammad, et al.
Publicado: (2013)

Alantolactone-loaded chitosan/hyaluronic acid nanoparticles suppress psoriasis by deactivating STAT3 pathway and restricting immune cell recruitment
por: Chen, Ruijie, et al.
Publicado: (2022)

Dual Targeting EGFR and STAT3 With Erlotinib and Alantolactone Co-Loaded PLGA Nanoparticles for Pancreatic Cancer Treatment
por: Bao, Shihui, et al.
Publicado: (2021)

Isolation, Characterization, Cryopreservation of Human Amniotic Stem Cells and Differentiation to Osteogenic and Adipogenic Cells
por: Gholizadeh-Ghaleh Aziz, Shiva, et al.
Publicado: (2016)

Alantolactone induces apoptosis, promotes STAT3 glutathionylation and enhances chemosensitivity of A549 lung adenocarcinoma cells to doxorubicin via oxidative stress
por: Maryam, Amara, et al.
Publicado: (2017)

Exosomes and COVID-19: challenges and opportunities
por: Babaei, Ghader, et al.
Publicado: (2022)

Combination effects of capecitabine, irinotecan and 17-AAG on colorectal cancer cell line (HT-29)
por: Zeynali-Moghaddam, Shima, et al.
Publicado: (2022)

Triggering of Programmed Erythrocyte Death by Alantolactone
por: Alzoubi, Kousi, et al.
Publicado: (2014)

Granzyme M expressed by tumor cells promotes chemoresistance and EMT in vitro and metastasis in vivo associated with STAT3 activation
por: Wang, Huiru, et al.
Publicado: (2015)

Alantolactone selectively ablates acute myeloid leukemia stem and progenitor cells
por: Ding, Yahui, et al.
Publicado: (2016)

Targeting Apoptosis Pathways in Cancer with Alantolactone and Isoalantolactone
por: Rasul, Azhar, et al.
Publicado: (2013)

Alantolactone suppresses human osteosarcoma through the PI3K/AKT signaling pathway
por: Zhang, Yong, et al.
Publicado: (2020)

Role of JAK/STAT3 Signaling in the Regulation of Metastasis, the Transition of Cancer Stem Cells, and Chemoresistance of Cancer by Epithelial–Mesenchymal Transition
por: Jin, Wook
Publicado: (2020)

Natural Product Alantolactone Targeting AKR1C1 Suppresses Cell Proliferation and Metastasis in Non-Small-Cell Lung Cancer
por: Fu, Zhiwen, et al.
Publicado: (2022)

Correction to: Alantolactone selectively ablates acute myeloid leukemia stem and progenitor cells
por: Ding, Yahui, et al.
Publicado: (2021)

JAKs and STATs in chemoresistance
por: Costa-Pereira, Ana P
Publicado: (2010)

Alantolactone inhibits proliferation, metastasis and promotes apoptosis of human osteosarcoma cells by suppressing Wnt/β-catenin and MAPKs signaling pathways
por: Yang, Chunmei, et al.
Publicado: (2020)

Overcoming Chemoresistance of Pediatric Ependymoma by Inhibition of STAT3 Signaling
por: Phi, Ji Hoon, et al.
Publicado: (2015)

Stem Extract from Momordica cochinchinensis Induces Apoptosis in Chemoresistant Human Prostate Cancer Cells (PC-3)
por: Chainumnim, Seksom, et al.
Publicado: (2022)

The Hepatotoxicity of Alantolactone and Germacrone: Their Influence on Cholesterol and Lipid Metabolism in Differentiated HepaRG Cells
por: Zárybnický, Tomáš, et al.
Publicado: (2020)

FBP1 regulates proliferation, metastasis, and chemoresistance by participating in C-MYC/STAT3 signaling axis in ovarian cancer
por: Li, Haoran, et al.
Publicado: (2021)

Microwave-assisted Extraction of Alantolactone and Isoalantolactone from Inula helenium
por: Zhao, Y. M., et al.
Publicado: (2015)

Alantolactone inhibits cervical cancer progression by downregulating BMI1
por: Sun, Xiaodong, et al.
Publicado: (2021)

Bidirectional and Opposite Effects of Naïve Mesenchymal Stem Cells on Tumor Growth and Progression
por: Rahmatizadeh, Faramarz, et al.
Publicado: (2019)

Targeting the gp130/STAT3 Axis Attenuates Tumor Microenvironment Mediated Chemoresistance in Group 3 Medulloblastoma Cells
por: Sreenivasan, Lakshana, et al.
Publicado: (2022)

Overexpression of RPS27a contributes to enhanced chemoresistance of CML cells to imatinib by the transactivated STAT3
por: Wang, Houcai, et al.
Publicado: (2016)

Glycochenodeoxycholic acid induces stemness and chemoresistance via the STAT3 signaling pathway in hepatocellular carcinoma cells
por: Shi, Changying, et al.
Publicado: (2020)

Induction of ROS Overload by Alantolactone Prompts Oxidative DNA Damage and Apoptosis in Colorectal Cancer Cells
por: Ding, Yushuang, et al.
Publicado: (2016)

Neuroprotective mechanism of low-dose sodium nitrite in oxygen-glucose deprivation model of cerebral ischemic stroke in PC12 cells
por: Shakib, Nader, et al.
Publicado: (2019)

Ultrasound-assisted extraction of alantolactone and isoalantolactone from Inula helenium roots
por: Trendafilova, Antoaneta, et al.
Publicado: (2010)

Cannot write session to /tmp/vufind_sessions/sess_tdeh07n8os11gh3gkcu9laerqh