Prediction of Metabolite Concentrations, Rate Constants and Post-Translational Regulation Using Maximum Entropy-Based Simulations with Application to Central Metabolism of Neurospora crassa

We report the application of a recently proposed approach for modeling biological systems using a maximum entropy production rate principle in lieu of having in vivo rate constants. The method is applied in four steps: (1) a new ordinary differential equation (ODE) based optimization approach based...

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Detalles Bibliográficos
Autores principales: Cannon, William R., Zucker, Jeremy D., Baxter, Douglas J., Kumar, Neeraj, Baker, Scott E., Hurley, Jennifer M., Dunlap, Jay C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8020867/
https://www.ncbi.nlm.nih.gov/pubmed/33824861
http://dx.doi.org/10.3390/pr6060063

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8020867/
https://www.ncbi.nlm.nih.gov/pubmed/33824861
http://dx.doi.org/10.3390/pr6060063

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