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TAR DNA-Binding Protein 43 Is Associated with Rate of Memory, Functional and Global Cognitive Decline in the Decade Prior to Death
BACKGROUND: Transactive response DNA-binding protein of 43 kDa (TDP-43) is associated with memory impairment and overall cognitive decline. It is unclear how TDP-43 contributes to the rate of clinical decline. OBJECTIVE: To determine whether cross-sectional and longitudinal cognitive and functional...
Autores principales: | Buciuc, Marina, Tosakulwong, Nirubol, Machulda, Mary M., Whitwell, Jennifer L., Weigand, Stephen D., Murray, Melissa E., Reichard, R. Ross, Parisi, Joseph E., Dickson, Dennis W., Boeve, Bradley F., Knopman, David S., Petersen, Ronald C., Josephs, Keith A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
IOS Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8020877/ https://www.ncbi.nlm.nih.gov/pubmed/33579840 http://dx.doi.org/10.3233/JAD-201166 |
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