Ultrapotent bispecific antibodies neutralize emerging SARS-CoV-2 variants

The emergence of SARS-CoV-2 variants that threaten the efficacy of existing vaccines and therapeutic antibodies underscores the urgent need for new antibody-based tools that potently neutralize variants by targeting multiple sites of the spike protein. We isolated 216 monoclonal antibodies targeting...

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Detalles Bibliográficos
Autores principales: Cho, Hyeseon, Gonzales-Wartz, Kristina Kay, Huang, Deli, Yuan, Meng, Peterson, Mary, Liang, Janie, Beutler, Nathan, Torres, Jonathan L., Cong, Yu, Postnikova, Elena, Bangaru, Sandhya, Talana, Chloe Adrienna, Shi, Wei, Yang, Eun Sung, Zhang, Yi, Leung, Kwanyee, Wang, Lingshu, Peng, Linghang, Skinner, Jeff, Li, Shanping, Wu, Nicholas C., Liu, Hejun, Dacon, Cherrelle, Moyer, Thomas, Cohen, Melanie, Zhao, Ming, Lee, F. Eun-Hyung, Weinberg, Rona S., Douagi, Iyadh, Gross, Robin, Schmaljohn, Connie, Pegu, Amarendra, Mascola, John R., Holbrook, Michael, Nemazee, David, Rogers, Thomas F., Ward, Andrew B., Wilson, Ian A., Crompton, Peter D., Tan, Joshua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8020967/
https://www.ncbi.nlm.nih.gov/pubmed/33821267
http://dx.doi.org/10.1101/2021.04.01.437942

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8020967/
https://www.ncbi.nlm.nih.gov/pubmed/33821267
http://dx.doi.org/10.1101/2021.04.01.437942

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