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Characterization of quinoxaline derivatives for protection against iatrogenically induced hearing loss

Hair cell loss is the leading cause of hearing and balance disorders in humans. It can be caused by many factors, including noise, aging, and therapeutic agents. Previous studies have shown the therapeutic potential of quinoxaline against drug-induced ototoxicity. Here, we screened a library of 68 q...

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Detalles Bibliográficos
Autores principales: Zallocchi, Marisa, Hati, Santanu, Xu, Zhenhang, Hausman, William, Liu, Huizhan, He, David Z., Zuo, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8021103/
https://www.ncbi.nlm.nih.gov/pubmed/33476306
http://dx.doi.org/10.1172/jci.insight.141561