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Expansion of donor-unrestricted MAIT cells with enhanced cytolytic function suitable for TCR redirection
Progress in our understanding of MR1-restricted mucosa-associated invariant T (MAIT) cells has raised interest in harnessing these cells for immunotherapy. The innate-like response characteristics, abundance in the blood, donor-unrestricted nature, and tropism for tissues make MAIT cells suitable ca...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Clinical Investigation
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8021122/ https://www.ncbi.nlm.nih.gov/pubmed/33561009 http://dx.doi.org/10.1172/jci.insight.140074 |