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Expansion of donor-unrestricted MAIT cells with enhanced cytolytic function suitable for TCR redirection

Progress in our understanding of MR1-restricted mucosa-associated invariant T (MAIT) cells has raised interest in harnessing these cells for immunotherapy. The innate-like response characteristics, abundance in the blood, donor-unrestricted nature, and tropism for tissues make MAIT cells suitable ca...

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Detalles Bibliográficos
Autores principales:	Parrot, Tiphaine, Healy, Katie, Boulouis, Caroline, Sobkowiak, Michał J., Leeansyah, Edwin, Aleman, Soo, Bertoletti, Antonio, Sällberg Chen, Margaret, Sandberg, Johan K.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Clinical Investigation 2021
Materias:	Technical Advance
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8021122/ https://www.ncbi.nlm.nih.gov/pubmed/33561009 http://dx.doi.org/10.1172/jci.insight.140074

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