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Interferon-λ3 Exacerbates the Inflammatory Response to Microbial Ligands: Implications for SARS-CoV-2 Pathogenesis

INTRODUCTION: Interferon lambdas (IFN-λs) are antiviral cytokines that restrict pathogen infection and dissemination at barrier surfaces. Controlled expression of IFN-λs efficiently eliminates acute infections by activating a suite of interferon stimulated genes that inhibit viral propagation and ac...

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Detalles Bibliográficos
Autores principales: Read, Scott A, Gloss, Brian S, Liddle, Christopher, George, Jacob, Ahlenstiel, Golo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8021260/
https://www.ncbi.nlm.nih.gov/pubmed/33833547
http://dx.doi.org/10.2147/JIR.S301476