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Interferon-λ3 Exacerbates the Inflammatory Response to Microbial Ligands: Implications for SARS-CoV-2 Pathogenesis
INTRODUCTION: Interferon lambdas (IFN-λs) are antiviral cytokines that restrict pathogen infection and dissemination at barrier surfaces. Controlled expression of IFN-λs efficiently eliminates acute infections by activating a suite of interferon stimulated genes that inhibit viral propagation and ac...
Autores principales: | Read, Scott A, Gloss, Brian S, Liddle, Christopher, George, Jacob, Ahlenstiel, Golo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8021260/ https://www.ncbi.nlm.nih.gov/pubmed/33833547 http://dx.doi.org/10.2147/JIR.S301476 |
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