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Control strategies to manage trade-offs during microbial production

When engineering microbes to overproduce a target molecule, engineers face multiple layers of trade-offs to allocate limited cellular resources between the target pathway and native cellular systems. These trade-offs arise from limited free ribosomes during translation, competition for metabolic pre...

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Detalles Bibliográficos
Autores principales: Han, Yichao, Zhang, Fuzhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8021483/
https://www.ncbi.nlm.nih.gov/pubmed/32810759
http://dx.doi.org/10.1016/j.copbio.2020.07.004