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Control strategies to manage trade-offs during microbial production
When engineering microbes to overproduce a target molecule, engineers face multiple layers of trade-offs to allocate limited cellular resources between the target pathway and native cellular systems. These trade-offs arise from limited free ribosomes during translation, competition for metabolic pre...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8021483/ https://www.ncbi.nlm.nih.gov/pubmed/32810759 http://dx.doi.org/10.1016/j.copbio.2020.07.004 |