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pH-Responsive Amphiphilic Carboxylate Polymers: Design and Potential for Endosomal Escape
The intracellular delivery of emerging biomacromolecular therapeutics, such as genes, peptides, and proteins, remains a great challenge. Unlike small hydrophobic drugs, these biotherapeutics are impermeable to the cell membrane, thus relying on the endocytic pathways for cell entry. After endocytosi...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Frontiers Media S.A.
2021
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8021698/ https://www.ncbi.nlm.nih.gov/pubmed/33834015 http://dx.doi.org/10.3389/fchem.2021.645297 |