Multiparametric flow cytometry highlights B7-H3 as a novel diagnostic/therapeutic target in GD2neg/low neuroblastoma variants

BACKGROUND: High-risk neuroblastomas (HR-NBs) are rare, aggressive pediatric cancers characterized by resistance to therapy and relapse in more than 30% of cases, despite using an aggressive therapeutic protocol including targeting of GD2. The mechanisms responsible for therapy resistance are unclea...

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Detalles Bibliográficos
Autores principales: Dondero, Alessandra, Morini, Martina, Cangelosi, Davide, Mazzocco, Katia, Serra, Martina, Spaggiari, Grazia Maria, Rotta, Gianluca, Tondo, Annalisa, Locatelli, Franco, Castellano, Aurora, Scuderi, Francesca, Sementa, Angela Rita, Eva, Alessandra, Conte, Massimo, Garaventa, Alberto, Bottino, Cristina, Castriconi, Roberta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2021
Materias:
Immunotherapy Biomarkers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8021887/
https://www.ncbi.nlm.nih.gov/pubmed/33795387
http://dx.doi.org/10.1136/jitc-2020-002293

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8021887/
https://www.ncbi.nlm.nih.gov/pubmed/33795387
http://dx.doi.org/10.1136/jitc-2020-002293

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