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Efficacy of Combined in-vivo Electroporation-Mediated Gene Transfer of VEGF, HGF, and IL-10 on Skin Flap Survival, Monitored by Label-Free Optical Imaging: A Feasibility Study

Preventing surgical flaps necrosis remains challenging. Laser Doppler imaging and ultrasound can monitor blood flow in flap regions, but they do not directly measure the cellular response to ischemia. The study aimed to investigate the efficacy of synergistic in-vivo electroporation-mediated gene tr...

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Detalles Bibliográficos
Autores principales: Seyed Jafari, S. Morteza, Blank, Fabian, Ramser, Hallie E., Woessner, Alan E., Shafighi, Maziar, Geiser, Thomas, Quinn, Kyle P., Hunger, Robert E., Gazdhar, Amiq
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8021947/
https://www.ncbi.nlm.nih.gov/pubmed/33834037
http://dx.doi.org/10.3389/fsurg.2021.639661