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Identification of NY-ESO-1(157–165) Specific Murine T Cell Receptors With Distinct Recognition Pattern for Tumor Immunotherapy

New York esophageal squamous cell carcinoma 1 (NY-ESO-1) is a promising target for T-cell receptor-engineered T cell (TCR-T) therapy, and targeting the human leukocyte antigen (HLA)-A2 restricted NY-ESO-1(157−165) epitope has yielded remarkable clinical benefits in the treatment of multiple advanced...

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Detalles Bibliográficos
Autores principales: Zhang, Helin, Sun, Meng, Wang, Jie, Zeng, Bin, Cao, Xiaoqing, Han, Yi, Tan, Shuguang, Gao, George F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8021954/
https://www.ncbi.nlm.nih.gov/pubmed/33833762
http://dx.doi.org/10.3389/fimmu.2021.644520