Cargando…

DNA with zwitterionic and negatively charged phosphate modifications: Formation of DNA triplexes, duplexes and cell uptake studies

Two phosphate modifications were introduced into the DNA backbone using the Staudinger reaction between the 3’,5’-dinucleoside β-cyanoethyl phosphite triester formed during DNA synthesis and sulfonyl azides, 4-(azidosulfonyl)-N,N,N-trimethylbutan-1-aminium iodide (N+ azide) or p-toluenesulfonyl (tos...

Descripción completa

Detalles Bibliográficos
Autores principales: Su, Yongdong, Bayarjargal, Maitsetseg, Hale, Tracy K, Filichev, Vyacheslav V
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Beilstein-Institut 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8022206/
https://www.ncbi.nlm.nih.gov/pubmed/33828619
http://dx.doi.org/10.3762/bjoc.17.65