Transient non-specific DNA binding dominates the target search of bacterial DNA-binding proteins

Despite their diverse biochemical characteristics and functions, all DNA-binding proteins share the ability to accurately locate their target sites among the vast excess of non-target DNA. Toward identifying universal mechanisms of the target search, we used single-molecule tracking of 11 diverse DN...

Descripción completa

Detalles Bibliográficos
Autores principales: Stracy, Mathew, Schweizer, Jakob, Sherratt, David J., Kapanidis, Achillefs N., Uphoff, Stephan, Lesterlin, Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8022225/
https://www.ncbi.nlm.nih.gov/pubmed/33621478
http://dx.doi.org/10.1016/j.molcel.2021.01.039

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8022225/
https://www.ncbi.nlm.nih.gov/pubmed/33621478
http://dx.doi.org/10.1016/j.molcel.2021.01.039

Ejemplares similares