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Transient non-specific DNA binding dominates the target search of bacterial DNA-binding proteins
Despite their diverse biochemical characteristics and functions, all DNA-binding proteins share the ability to accurately locate their target sites among the vast excess of non-target DNA. Toward identifying universal mechanisms of the target search, we used single-molecule tracking of 11 diverse DN...
Autores principales: | Stracy, Mathew, Schweizer, Jakob, Sherratt, David J., Kapanidis, Achillefs N., Uphoff, Stephan, Lesterlin, Christian |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cell Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8022225/ https://www.ncbi.nlm.nih.gov/pubmed/33621478 http://dx.doi.org/10.1016/j.molcel.2021.01.039 |
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