Hepatic deletion of Mboat7 (LPIAT1) causes activation of SREBP-1c and fatty liver

Genetic variants that increase the risk of fatty liver disease and cirrhosis have recently been identified in the proximity of membrane-bound O-acyltransferase domain-containing 7 (MBOAT7). To elucidate the link between these variants and fatty liver disease, we characterized Mboat7 liver-specific K...

Descripción completa

Detalles Bibliográficos
Autores principales: Xia, Mingfeng, Chandrasekaran, Preethi, Rong, Shunxing, Fu, Xiaorong, Mitsche, Matthew A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8022244/
https://www.ncbi.nlm.nih.gov/pubmed/32859645
http://dx.doi.org/10.1194/jlr.RA120000856

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8022244/
https://www.ncbi.nlm.nih.gov/pubmed/32859645
http://dx.doi.org/10.1194/jlr.RA120000856

Ejemplares similares