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Hepatic deletion of Mboat7 (LPIAT1) causes activation of SREBP-1c and fatty liver

Genetic variants that increase the risk of fatty liver disease and cirrhosis have recently been identified in the proximity of membrane-bound O-acyltransferase domain-containing 7 (MBOAT7). To elucidate the link between these variants and fatty liver disease, we characterized Mboat7 liver-specific K...

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Detalles Bibliográficos
Autores principales:	Xia, Mingfeng, Chandrasekaran, Preethi, Rong, Shunxing, Fu, Xiaorong, Mitsche, Matthew A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8022244/ https://www.ncbi.nlm.nih.gov/pubmed/32859645 http://dx.doi.org/10.1194/jlr.RA120000856

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