Structural basis for conformational equilibrium of the catalytic spliceosome

The ATPase Prp16 governs equilibrium between the branching (B(∗)/C) and exon ligation (C(∗)/P) conformations of the spliceosome. Here, we present the electron cryomicroscopy reconstruction of the Saccharomyces cerevisiae C-complex spliceosome at 2.8 Å resolution and identify a novel C-complex interm...

Descripción completa

Detalles Bibliográficos
Autores principales: Wilkinson, Max E., Fica, Sebastian M., Galej, Wojciech P., Nagai, Kiyoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8022279/
https://www.ncbi.nlm.nih.gov/pubmed/33705709
http://dx.doi.org/10.1016/j.molcel.2021.02.021

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8022279/
https://www.ncbi.nlm.nih.gov/pubmed/33705709
http://dx.doi.org/10.1016/j.molcel.2021.02.021

Ejemplares similares