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Comparing the Efficacy of Cancer Therapies between Subgroups in Basket Trials

The need to test anticancer drugs in multiple indications has been addressed by basket trials, which are Phase I or II clinical trials involving multiple tumor subtypes and a single master protocol. Basket trials typically involve few patients per type, making it challenging to rigorously compare re...

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Detalles Bibliográficos
Autores principales: Palmer, Adam C., Plana, Deborah, Sorger, Peter K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8022348/
https://www.ncbi.nlm.nih.gov/pubmed/33220857
http://dx.doi.org/10.1016/j.cels.2020.09.003