GSK3β rephosphorylation rescues ALPL deficiency-induced impairment of odontoblastic differentiation of DPSCs

BACKGROUND: Premature exfoliation of the deciduous teeth is a common manifestation in childhood patients with hypophosphatasia (HPP), which is an autosomal inherited disease caused by ALPL mutations. Dysplasia of the cementum, dentin, and alveolar bone has been proposed to be the main reasons for th...

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Detalles Bibliográficos
Autores principales: Zhang, Liqiang, Zhao, Jiangdong, Dong, Jiayi, Liu, Yuting, Xuan, Kun, Liu, Wenjia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8022410/
https://www.ncbi.nlm.nih.gov/pubmed/33823913
http://dx.doi.org/10.1186/s13287-021-02235-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8022410/
https://www.ncbi.nlm.nih.gov/pubmed/33823913
http://dx.doi.org/10.1186/s13287-021-02235-7

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