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Exosomes derived from miR-26a-modified MSCs promote axonal regeneration via the PTEN/AKT/mTOR pathway following spinal cord injury

BACKGROUND: Exosomes derived from the bone marrow mesenchymal stem cell (MSC) have shown great potential in spinal cord injury (SCI) treatment. This research was designed to investigate the therapeutic effects of miR-26a-modified MSC-derived exosomes (Exos-26a) following SCI. METHODS: Bioinformatics...

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Detalles Bibliográficos
Autores principales: Chen, Yuyong, Tian, Zhenming, He, Lei, Liu, Can, Wang, Nangxiang, Rong, Limin, Liu, Bin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8022427/
https://www.ncbi.nlm.nih.gov/pubmed/33820561
http://dx.doi.org/10.1186/s13287-021-02282-0