FlyORF-TaDa allows rapid generation of new lines for in vivo cell-type-specific profiling of protein–DNA interactions in Drosophila melanogaster

Targeted DamID (TaDa) is an increasingly popular method of generating cell-type-specific DNA-binding profiles in vivo. Although sensitive and versatile, TaDa requires the generation of new transgenic fly lines for every protein that is profiled, which is both time-consuming and costly. Here, we desc...

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Detalles Bibliográficos
Autores principales: Aughey, Gabriel N, Delandre, Caroline, McMullen, John P D, Southall, Tony D, Marshall, Owen J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Investigation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8022459/
https://www.ncbi.nlm.nih.gov/pubmed/33561239
http://dx.doi.org/10.1093/g3journal/jkaa005

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8022459/
https://www.ncbi.nlm.nih.gov/pubmed/33561239
http://dx.doi.org/10.1093/g3journal/jkaa005

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