TREM2/PLCγ2 signalling in immune cells: function, structural insight, and potential therapeutic modulation

The central role of the resident innate immune cells of the brain (microglia) in neurodegeneration has become clear over the past few years largely through genome-wide association studies (GWAS), and has rapidly become an active area of research. However, a mechanistic understanding (gene to functio...

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Detalles Bibliográficos
Autores principales: Magno, Lorenza, Bunney, Tom D., Mead, Emma, Svensson, Fredrik, Bictash, Magda N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8022522/
https://www.ncbi.nlm.nih.gov/pubmed/33823896
http://dx.doi.org/10.1186/s13024-021-00436-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8022522/
https://www.ncbi.nlm.nih.gov/pubmed/33823896
http://dx.doi.org/10.1186/s13024-021-00436-5

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