TREM2/PLCγ2 signalling in immune cells: function, structural insight, and potential therapeutic modulation

The central role of the resident innate immune cells of the brain (microglia) in neurodegeneration has become clear over the past few years largely through genome-wide association studies (GWAS), and has rapidly become an active area of research. However, a mechanistic understanding (gene to functio...

Fuld beskrivelse

Bibliografiske detaljer
Autores principales: Magno, Lorenza, Bunney, Tom D., Mead, Emma, Svensson, Fredrik, Bictash, Magda N.
Format: Online Artículo Texto
Sprog:English
Udgivet: BioMed Central 2021
Fag:
Review
Online adgang:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8022522/
https://www.ncbi.nlm.nih.gov/pubmed/33823896
http://dx.doi.org/10.1186/s13024-021-00436-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8022522/
https://www.ncbi.nlm.nih.gov/pubmed/33823896
http://dx.doi.org/10.1186/s13024-021-00436-5

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