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TREM2/PLCγ2 signalling in immune cells: function, structural insight, and potential therapeutic modulation
The central role of the resident innate immune cells of the brain (microglia) in neurodegeneration has become clear over the past few years largely through genome-wide association studies (GWAS), and has rapidly become an active area of research. However, a mechanistic understanding (gene to functio...
| Autores principales: | , , , , |
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| Formato: | Online Artigo Texto |
| Idioma: | English |
| Publicado: |
BioMed Central
2021
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| Materias: | |
| Acceso en liña: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8022522/ https://www.ncbi.nlm.nih.gov/pubmed/33823896 http://dx.doi.org/10.1186/s13024-021-00436-5 |