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TREM2/PLCγ2 signalling in immune cells: function, structural insight, and potential therapeutic modulation

The central role of the resident innate immune cells of the brain (microglia) in neurodegeneration has become clear over the past few years largely through genome-wide association studies (GWAS), and has rapidly become an active area of research. However, a mechanistic understanding (gene to functio...

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Detaylı Bibliyografya
Asıl Yazarlar: Magno, Lorenza, Bunney, Tom D., Mead, Emma, Svensson, Fredrik, Bictash, Magda N.
Materyal Türü: Online Makale Metin
Dil:English
Baskı/Yayın Bilgisi: BioMed Central 2021
Konular:
Online Erişim:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8022522/
https://www.ncbi.nlm.nih.gov/pubmed/33823896
http://dx.doi.org/10.1186/s13024-021-00436-5