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Influence of high pressure compaction on solubility and intrinsic dissolution of ibuprofen binary mixtures employing standard excipients

Enabling formulations often depend on functional excipients. However, the question remains whether excipients regarded as standard establish similar interactions and subsequently improvement of solubility when employed at unusual manufacturing process conditions. In this study, compaction of API und...

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Detalles Bibliográficos
Autores principales: Ibraheem, Bashar, Wagner, Karl G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8022821/
https://www.ncbi.nlm.nih.gov/pubmed/33851132
http://dx.doi.org/10.1016/j.ijpx.2021.100075