Application of an optimized annotation pipeline to the Cryptococcus deuterogattii genome reveals dynamic primary metabolic gene clusters and genomic impact of RNAi loss

Evaluating the quality of a de novo annotation of a complex fungal genome based on RNA-seq data remains a challenge. In this study, we sequentially optimized a Cufflinks-CodingQuary-based bioinformatics pipeline fed with RNA-seq data using the manually annotated model pathogenic yeasts Cryptococcus...

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Detalles Bibliográficos
Autores principales: Gröhs Ferrareze, Patrícia Aline, Maufrais, Corinne, Silva Araujo Streit, Rodrigo, Priest, Shelby J, Cuomo, Christina A, Heitman, Joseph, Staats, Charley Christian, Janbon, Guilhem
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Fungal Genetics and Genomics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8022950/
https://www.ncbi.nlm.nih.gov/pubmed/33585873
http://dx.doi.org/10.1093/g3journal/jkaa070

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8022950/
https://www.ncbi.nlm.nih.gov/pubmed/33585873
http://dx.doi.org/10.1093/g3journal/jkaa070

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