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Treatment of the X chromosome in mapping multiple quantitative trait loci

Statistical methods to map quantitative trait loci (QTL) often neglect the X chromosome and may focus exclusively on autosomal loci. But the X chromosome often requires special treatment: sex and cross-direction covariates may need to be included to avoid spurious evidence of linkage, and the X chro...

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Detalles Bibliográficos
Autores principales: Tran, Quoc, Broman, Karl W
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8022961/
https://www.ncbi.nlm.nih.gov/pubmed/33604671
http://dx.doi.org/10.1093/g3journal/jkab005