License to kill: microsatellite instability and immune contexture

Colorectal cancers (CRCs) with microsatellite instability (MSI) are due to a defect in the DNA mismatch repair (MMR) system resulting in an accumulation of frame-shift mutations. They are characterized by a tumor microenvironment richer in cytotoxic CD8 T-cells (CTLs) and a better prognosis compared...

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Detalles Bibliográficos
Autores principales: Maby, Pauline, Bindea, Gabriela, Mlecnik, Bernhard, Galon, Jérôme
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Author’s View
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8023238/
https://www.ncbi.nlm.nih.gov/pubmed/33868790
http://dx.doi.org/10.1080/2162402X.2021.1905935

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8023238/
https://www.ncbi.nlm.nih.gov/pubmed/33868790
http://dx.doi.org/10.1080/2162402X.2021.1905935

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