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Hedgehog signaling and Tre1 regulate actin dynamics through PI(4,5)P(2) to direct migration of Drosophila embryonic germ cells

The Tre1 G-protein coupled receptor (GPCR) was discovered to be required for Drosophila germ cell (GC) coalescence almost two decades ago, yet the molecular events both upstream and downstream of Tre1 activation remain poorly understood. To gain insight into these events, we describe a bona fide nul...

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Detalles Bibliográficos
Autores principales: Kim, Ji Hoon, Hanlon, Caitlin D., Vohra, Sunaina, Devreotes, Peter N., Andrew, Deborah J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8023404/
https://www.ncbi.nlm.nih.gov/pubmed/33657369
http://dx.doi.org/10.1016/j.celrep.2021.108799