Enhancing glucose metabolism via gluconeogenesis is therapeutic in a zebrafish model of Dravet syndrome

Energy-producing pathways are novel therapeutic targets for the treatment of neurodevelopmental disorders. Here, we focussed on correcting metabolic defects in a catastrophic paediatric epilepsy, Dravet syndrome which is caused by mutations in sodium channel NaV1.1 gene, SCN1A. We utilized a transla...

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Detalles Bibliográficos
Autores principales: Banerji, Rajeswari, Huynh, Christopher, Figueroa, Francisco, Dinday, Matthew T, Baraban, Scott C, Patel, Manisha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8023476/
https://www.ncbi.nlm.nih.gov/pubmed/33842883
http://dx.doi.org/10.1093/braincomms/fcab004

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8023476/
https://www.ncbi.nlm.nih.gov/pubmed/33842883
http://dx.doi.org/10.1093/braincomms/fcab004

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