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Enhancing glucose metabolism via gluconeogenesis is therapeutic in a zebrafish model of Dravet syndrome

Energy-producing pathways are novel therapeutic targets for the treatment of neurodevelopmental disorders. Here, we focussed on correcting metabolic defects in a catastrophic paediatric epilepsy, Dravet syndrome which is caused by mutations in sodium channel NaV1.1 gene, SCN1A. We utilized a transla...

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Detalles Bibliográficos
Autores principales:	Banerji, Rajeswari, Huynh, Christopher, Figueroa, Francisco, Dinday, Matthew T, Baraban, Scott C, Patel, Manisha
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2021
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8023476/ https://www.ncbi.nlm.nih.gov/pubmed/33842883 http://dx.doi.org/10.1093/braincomms/fcab004

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