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Component of Cannabis, Cannabidiol, as a Possible Drug against the Cytotoxicity of Aβ(31–35) and Aβ(25–35) Peptides: An Investigation by Molecular Dynamics and Well-Tempered Metadynamics Simulations

[Image: see text] In this work cannabidiol (CBD) was investigated as a possible drug against the cytotoxicity of Aβ(31–35) and Aβ(25–35) peptides with the help of atomistic molecular dynamics (MD) and well-tempered metadynamics simulations. Four interrelated mechanisms of possible actions of CBD are...

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Detalles Bibliográficos
Autores principales: Chrobak, Wojciech, Pacut, Dawid Wojciech, Blomgren, Fredrik, Rodin, Alexander, Swenson, Jan, Ermilova, Inna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8023578/
https://www.ncbi.nlm.nih.gov/pubmed/33544587
http://dx.doi.org/10.1021/acschemneuro.0c00692