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Insights into the Dynamics of the Human Zinc Transporter ZnT8 by MD Simulations

[Image: see text] ZnT8 is a human zinc(II) transporter expressed at the membrane of secretory granules where it contributes to insulin storage importing zinc ions from the cytosol. In the human population, the two most common ZnT8 variants carry an arginine (R325) or a tryptophan (W325) in position...

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Detalles Bibliográficos
Autores principales: Sala, Davide, Giachetti, Andrea, Rosato, Antonio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8023586/
https://www.ncbi.nlm.nih.gov/pubmed/33508935
http://dx.doi.org/10.1021/acs.jcim.0c01139