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Simplified MethylRAD Sequencing to Detect Changes in DNA Methylation at Enhancer Elements in Differentiating Embryonic Stem Cells

Differential DNA methylation is characteristic of gene regulatory regions, such as enhancers, which mostly constitute low or intermediate CpG content in their DNA sequence. Consequently, quantification of changes in DNA methylation at these sites is challenging. Given that DNA methylation across mos...

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Detalles Bibliográficos
Autores principales: Saha, Debapriya, Norvil, Allison B., Lanman, Nadia A., Gowher, Humaira
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8023688/
https://www.ncbi.nlm.nih.gov/pubmed/33828860
http://dx.doi.org/10.3390/epigenomes4040024