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Carboxylesterase Activities and Protein Expression in Rabbit and Pig Ocular Tissues
[Image: see text] Hydrolytic reactions constitute an important pathway of drug metabolism and a significant route of prodrug activation. Many ophthalmic drugs and prodrugs contain ester groups that greatly enhance their permeation across several hydrophobic barriers in the eye before the drugs are e...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical
Society
2021
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8023712/ https://www.ncbi.nlm.nih.gov/pubmed/33595329 http://dx.doi.org/10.1021/acs.molpharmaceut.0c01154 |