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Carboxylesterase Activities and Protein Expression in Rabbit and Pig Ocular Tissues
[Image: see text] Hydrolytic reactions constitute an important pathway of drug metabolism and a significant route of prodrug activation. Many ophthalmic drugs and prodrugs contain ester groups that greatly enhance their permeation across several hydrophobic barriers in the eye before the drugs are e...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical
Society
2021
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8023712/ https://www.ncbi.nlm.nih.gov/pubmed/33595329 http://dx.doi.org/10.1021/acs.molpharmaceut.0c01154 |