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Maturation of Complex Synaptic Connections of Layer 5 Cortical Axons in the Posterior Thalamic Nucleus Requires SNAP25

Synapses are able to form in the absence of neuronal activity, but how is their subsequent maturation affected in the absence of regulated vesicular release? We explored this question using 3D electron microscopy and immunoelectron microscopy analyses in the large, complex synapses formed between co...

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Detalles Bibliográficos
Autores principales: Hayashi, Shuichi, Hoerder-Suabedissen, Anna, Kiyokage, Emi, Maclachlan, Catherine, Toida, Kazunori, Knott, Graham, Molnár, Zoltán
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8023812/
https://www.ncbi.nlm.nih.gov/pubmed/33367517
http://dx.doi.org/10.1093/cercor/bhaa379