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Excitation of medium spiny neurons by ‘inhibitory’ ultrapotent chemogenetics via shifts in chloride reversal potential
Ultrapotent chemogenetics, including the chloride-permeable inhibitory PSAM(4)-GlyR receptor, were recently proposed as a powerful strategy to selectively control neuronal activity in awake, behaving animals. We aimed to validate the inhibitory function of PSAM(4)-GlyR in dopamine D1 receptor-expres...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
eLife Sciences Publications, Ltd
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8024007/ https://www.ncbi.nlm.nih.gov/pubmed/33822716 http://dx.doi.org/10.7554/eLife.64241 |