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Excitation of medium spiny neurons by ‘inhibitory’ ultrapotent chemogenetics via shifts in chloride reversal potential

Ultrapotent chemogenetics, including the chloride-permeable inhibitory PSAM(4)-GlyR receptor, were recently proposed as a powerful strategy to selectively control neuronal activity in awake, behaving animals. We aimed to validate the inhibitory function of PSAM(4)-GlyR in dopamine D1 receptor-expres...

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Detalles Bibliográficos
Autores principales:	Gantz, Stephanie C, Ortiz, Maria M, Belilos, Andrew J, Moussawi, Khaled
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	eLife Sciences Publications, Ltd 2021
Materias:	Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8024007/ https://www.ncbi.nlm.nih.gov/pubmed/33822716 http://dx.doi.org/10.7554/eLife.64241

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