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Integron activity accelerates the evolution of antibiotic resistance

Mobile integrons are widespread genetic platforms that allow bacteria to modulate the expression of antibiotic resistance cassettes by shuffling their position from a common promoter. Antibiotic stress induces the expression of an integrase that excises and integrates cassettes, and this unique reco...

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Detalles Bibliográficos
Autores principales: Souque, Célia, Escudero, José Antonio, MacLean, R Craig
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8024014/
https://www.ncbi.nlm.nih.gov/pubmed/33634790
http://dx.doi.org/10.7554/eLife.62474