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Inhibiting ATP6V0D2 Aggravates Liver Ischemia-Reperfusion Injury by Promoting NLRP3 Activation via Impairing Autophagic Flux Independent of Notch1/Hes1

At present, liver ischemia-reperfusion (IR) injury is still a great challenge for clinical liver partial resection and liver transplantation. The innate immunity regulated by liver macrophages orchestrates the cascade of IR inflammation and acts as a bridge. As a specific macrophage subunit of vacuo...

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Detalles Bibliográficos
Autores principales: Wang, Ziyi, Wang, Hao, Chen, Xuejiao, Han, Sheng, Zhu, Yulin, Wang, Hanhua, Cheng, Feng, Pu, Liyong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8024071/
https://www.ncbi.nlm.nih.gov/pubmed/33860063
http://dx.doi.org/10.1155/2021/6670495