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Inhibiting ATP6V0D2 Aggravates Liver Ischemia-Reperfusion Injury by Promoting NLRP3 Activation via Impairing Autophagic Flux Independent of Notch1/Hes1
At present, liver ischemia-reperfusion (IR) injury is still a great challenge for clinical liver partial resection and liver transplantation. The innate immunity regulated by liver macrophages orchestrates the cascade of IR inflammation and acts as a bridge. As a specific macrophage subunit of vacuo...
Autores principales: | Wang, Ziyi, Wang, Hao, Chen, Xuejiao, Han, Sheng, Zhu, Yulin, Wang, Hanhua, Cheng, Feng, Pu, Liyong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8024071/ https://www.ncbi.nlm.nih.gov/pubmed/33860063 http://dx.doi.org/10.1155/2021/6670495 |
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